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2D pixel art? Have you heard of Monogame? It's all C# all day, so yeah you'll need to learn that. But it's also been used for a bunch of indie 2d pixel art games, so there's that too.
Or if you'd rather do a bit less coding, Construct 3 or GDevelop? Both of those are decent 2D engines with visual scripting. You can also try out both of them in the browser, so you can decide if you like them without having to download anything. (There are full local versions too, it's just convenient to be able to test something really quickly in a browser to see if you like it).
Fair warning, base Monogame leaves a lot to you to create yourself. It's technically a framework and not an engine (difference explained here). However, there are several extensions that add specific things you might want.
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