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:gem: An easy-to-use workflow for generating context specific genome-scale metabolic models and predicting metabolic interactions within microbial communities directly from metagenomic data
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Hi all, I made a post a while back advertising the metaGEM pipeline for reconstructing metagenome assembled genomes (MAGs) and genome scale metabolic models (GEMs) from metagenomes. The paper has now been published in Nucleic Acids Research, I hope some of you here may find it interesting or useful for your own research! I will also leave the GitHub repo here 💻 🧬
Regarding your question about a reference database, we have deposited the models in a zenodo repository for now (https://zenodo.org/record/4407746#.YWFXFBbRYWM), but I do plan on making them more accessible (e.g. https://github.com/cdanielmachado/embl_gems) and also providing the underlying genomes + taxonomic annotation and other info/metadata generated by metaGEM.
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