bwa VS foldseek

Compare bwa vs foldseek and see what are their differences.

bwa

Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment) (by lh3)

foldseek

Foldseek enables fast and sensitive comparisons of large structure sets. (by steineggerlab)
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bwa foldseek
3 1
1,453 637
- 6.0%
2.7 9.3
18 days ago 8 days ago
C C
GNU General Public License v3.0 only GNU General Public License v3.0 only
The number of mentions indicates the total number of mentions that we've tracked plus the number of user suggested alternatives.
Stars - the number of stars that a project has on GitHub. Growth - month over month growth in stars.
Activity is a relative number indicating how actively a project is being developed. Recent commits have higher weight than older ones.
For example, an activity of 9.0 indicates that a project is amongst the top 10% of the most actively developed projects that we are tracking.

bwa

Posts with mentions or reviews of bwa. We have used some of these posts to build our list of alternatives and similar projects. The last one was on 2023-05-25.

foldseek

Posts with mentions or reviews of foldseek. We have used some of these posts to build our list of alternatives and similar projects.
  • AI predicts shape of nearly every known protein
    1 project | news.ycombinator.com | 28 Jul 2022
    "Some sophisticated applications of the expanded AlphaFold database might also depend on downloading its entire 23 terabyte contents, which won’t be feasible for many teams, Steinegger says. Cloud-based storage could also prove costly. Steinegger has co-developed a software tool called FoldSeek that can quickly find structurally similar proteins and which should be able to squash the AlphaFold data down considerably."

    [FoldSeek Search](https://search.foldseek.com/search)

    [Github:FoldSeek](https://github.com/steineggerlab/foldseek)

What are some alternatives?

When comparing bwa and foldseek you can also consider the following projects:

slivar - genetic variant expressions, annotation, and filtering for great good.

DAGSfM - Distributed and Graph-based Structure from Motion. This project includes the official implementation of our Pattern Recognition 2020 paper: Graph-Based Parallel Large Scale Structure from Motion.

MethylDackel - A (mostly) universal methylation extractor for BS-seq experiments.

hh-suite - Remote protein homology detection suite.

sra-tools - SRA Tools

MooseFS - MooseFS – Open Source, Petabyte, Fault-Tolerant, Highly Performing, Scalable Network Distributed File System (Software-Defined Storage)

bowtie - An ultrafast memory-efficient short read aligner

mars - Asynchronous Block-Level Storage Replication

spades - SPAdes Genome Assembler

seqtk - Toolkit for processing sequences in FASTA/Q formats

libBigWig - A C library for handling bigWig files

javascript-obfuscator - A powerful obfuscator for JavaScript and Node.js