Top 14 Python Protocol Projects

lbry-sdk

1 167 7,204 5.1 Python

The LBRY SDK for building decentralized, censorship resistant, monetized digital content apps.
Judoscale

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pymobiledevice3

2 5 1,703 9.4 Python

Pure python3 implementation for working with iDevices (iPhone, etc...).

Project mention: Pymobiledevice3: A Pure Python3 Library for Seamless iDevice Management | news.ycombinator.com | 2024-09-03
opcua-asyncio

3 2 1,221 8.7 Python

OPC UA library for python >= 3.7
agent-protocol

4 4 1,171 4.1 Python

Common interface for interacting with AI agents. The protocol is tech stack agnostic - you can use it with any framework for building agents.
quarry

5 3 536 4.1 Python

Python library that implements the Minecraft network protocol and data types
pycomm3

6 6 440 0.0 Python

A Python Ethernet/IP library for communicating with Allen-Bradley PLCs.
api

7 5 146 9.6 Python

Building blocks for your blockchain economy (by moonstream-to)
CodeRabbit

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dataframe-api

8 2 106 8.6 Python

RFC document, tooling and other content related to the dataframe API standard
hal-9000

9 0 86 2.6 Python

Automatically setup a productive development environment with Ansible on macOS
stupidArtnet

10 1 83 5.3 Python

(Very) Simple Python library implementation of the Art-Net protocol
pocs_slides

11 1 63 4.2 Python

my advisory, poc, slides and scripts related to IoT/protocol security
monero-agent

12 4 27 0.0 Python

Monero hardware wallet protocol implementation for Trezor, agent
sniffer

13 2 4 8.7 Python

Network analyzer (by ksfi)
a2a-langgraph

14 1 0 4.0 Python

🤖💬🤖 Agent-to-Agent (A2A Protocol) built on top of LangGraph

Project mention: The Agent2Agent Protocol (A2A) | news.ycombinator.com | 2025-04-09

Example A2A Protocol built on top of LangGraph and Dockerized for deployments. If you find helpful drop a
https://github.com/enso-labs/a2a-langgraph
InfluxDB

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InfluxDB high-performance time series database. Collect, organize, and act on massive volumes of high-resolution data to power real-time intelligent systems.

NOTE: The open source projects on this list are ordered by number of github stars. The number of mentions indicates repo mentiontions in the last 12 Months or since we started tracking (Dec 2020).

Python Protocol discussion

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Bridging the Gap: Better Token Standards for Cross-chain Assets

4 projects | dev.to | 2 Nov 2023
api: NEW Data - star count:120.0

1 project | /r/algoprojects | 10 Jun 2023
api: NEW Data - star count:120.0

1 project | /r/algoprojects | 9 Jun 2023
api: NEW Data - star count:120.0

1 project | /r/algoprojects | 8 Jun 2023
api: NEW Data - star count:120.0

1 project | /r/algoprojects | 7 Jun 2023
Zippyshare is now Defunct o7

3 projects | /r/Piracy | 3 Apr 2023
API data to TIA

3 projects | /r/PLC | 1 Mar 2023
A note from our sponsor - Judoscale
judoscale.com | 17 Apr 2025

Judoscale integrates with Django, FastAPI, Celery, and RQ to make autoscaling easy and reliable. Save big, and say goodbye to request timeouts and backed-up task queues. Learn more →

Index

What are some of the best open-source Protocol projects in Python? This list will help you:

#	Project	Stars
1	lbry-sdk	7,204
2	pymobiledevice3	1,703
3	opcua-asyncio	1,221
4	agent-protocol	1,171
5	quarry	536
6	pycomm3	440
7	api	146
8	dataframe-api	106
9	hal-9000	86
10	stupidArtnet	83
11	pocs_slides	63
12	monero-agent	27
13	sniffer	4
14	a2a-langgraph	0