Top 23 Python Protocol Projects

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1. lbry-sdk

   1 168 7,175 5.1 Python

   The LBRY SDK for building decentralized, censorship resistant, monetized digital content apps.

   

   Project mention: Yt-dlp: Upcoming new requirements for YouTube downloads | news.ycombinator.com | 2025-09-24

   yeah there are alternatives for sure, but it takes time to discover them. But many search engine are offering searching of videos. So may just be a good idea to start building a public index of all the videos.

   And it is 2025, the HN crowd here can usually just deploy their video to CDN. Many business are also just hosting their own videos.

   BTW forgot to mention Odyssey underlying protocol is https://lbry.com

   And seems like there are past article about it on HN: https://news.ycombinator.com/item?id=24594663

2. SaaSHub

   www.saashub.com featured

   SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

   

3. pymobiledevice3

   2 5 2,618 9.7 Python

   Pure python3 implementation for working with iDevices (iPhone, etc...).

   

4. COMTool

   3 1 2,563 4.6 Python

   Cross platform communicate assistant(Serial/network/terminal tool)（ 跨平台 串口调试助手 网络调试助手 终端工具 linux windows mac Raspberry Pi ）支持插件和二次开发

   

   Project mention: Supply Chain Alert: Sipeed's Official COMTools Software Flagged as Trojan | news.ycombinator.com | 2025-11-10

5. agent-protocol

   4 4 1,463 4.1 Python

   Common interface for interacting with AI agents. The protocol is tech stack agnostic - you can use it with any framework for building agents.

   

6. opcua-asyncio

   5 2 1,453 9.3 Python

   OPC UA library for python >= 3.10

   

7. aiomqtt

   6 1 569 6.1 Python

   The idiomatic asyncio MQTT client

   

8. quarry

   7 3 550 4.1 Python

   Python library that implements the Minecraft network protocol and data types

   

9. pycomm3

   8 6 512 4.4 Python

   A Python Ethernet/IP library for communicating with Allen-Bradley PLCs.

   

10. dnscrypt-protocol

    9 4 171 7.6 Python

    DNSCrypt protocol specification

    

11. api

    10 5 149 9.6 Python

    Building blocks for your blockchain economy (by moonstream-to)

    

12. hal-9000

    11 1 124 9.9 Python

    Opinionated AI coding agent and dev environment automation for macOS

    

    Project mention: A Claude Code plugin that plays HAL 9000 voice clips on hook events | news.ycombinator.com | 2026-03-02

13. dataframe-api

    12 2 106 8.6 Python

    RFC document, tooling and other content related to the dataframe API standard

    

14. stupidArtnet

    13 1 98 5.3 Python

    (Very) Simple Python library implementation of the Art-Net protocol

    

15. pocs_slides

    14 1 71 2.0 Python

    my advisory, poc, slides and scripts related to IoT/protocol security

    

16. dcp

    15 1 51 8.5 Python

    Device Context Protocol — bridge LLM agents to physical devices. Sub-50-byte frames, 27.6KB flash / 0.6KB RAM measured on ESP32, capability-scoped and safe by design. Complementary to MCP. Paper: arXiv:2605.26159 (by device-context-protocol)

    

    Project mention: Device Context Protocol – Bridge LLM Agents to Physical Devices | news.ycombinator.com | 2026-07-13

17. translator

    16 1 51 8.6 Python

    layer that lets you connect any agent, any tool, any api together.

    

    Project mention: Show HN: Middleware for translating between AI agent protocols | news.ycombinator.com | 2026-03-17

18. formosa

    17 0 44 3.2 Python

    :snake: Improvement upon BIP39 --- changed from disconnected words to themed sentences

    

19. PANTHER

    18 1 42 9.8 Python

    This tool presents a novel approach to bolstering network protocol verification by integrating the Shadow network simulator with the Ivy formal verification tool to check time properties. Furthermore, it extends Ivy’s capabilities with a dedicated time module, enabling the verification of complex quantitative-time properties. (by ElNiak)

    

20. a2a-langgraph

    19 1 31 4.8 Python

    🤖💬🤖 Agent-to-Agent (A2A Protocol) built on top of LangGraph

    

21. monero-agent

    20 4 30 0.0 Python

    Monero hardware wallet protocol implementation for Trezor, agent

    

22. Great_Wall

    21 0 26 1.7 Python

    Protocol and application for providing Kerckhoffian, 0-trust, deviceless coercion-resistance in self-custody.

    

23. publsp

    22 0 22 8.5 Python

    LN liquidity offers/purchases over Nostr

    

24. mycelium

    23 5 18 8.3 Python

    🍄 The open-source internet for AI agents. pip install → discover → communicate → collaborate. (by udaysaai)

    

    Project mention: LangChain’s tool routing is a bloated mess. So we built a <10ms local semantic registry to replace it at US Neural. | dev.to | 2026-07-26

    GitHub & Reproducible Scripts: https://github.com/udaysaai/mycelium Visual Dashboard: https://mycelium-agents.netlify.app/

Python Protocol related posts

• I Put a $0.02 Paywall on My AI API. Here's What I Learned.

  3 projects | dev.to | 10 Mar 2026

• A Claude Code plugin that plays HAL 9000 voice clips on hook events

  1 project | news.ycombinator.com | 2 Mar 2026

• Evicting MCP tool calls from your Kubernetes cluster

  2 projects | dev.to | 2 Dec 2025

• ESP32 Bus Pirate 0.5 – A Hardware Hacking Tool That Speaks Every Protocol

  4 projects | news.ycombinator.com | 9 Aug 2025

• Bridging the Gap: Better Token Standards for Cross-chain Assets

  4 projects | dev.to | 2 Nov 2023

• api: NEW Data - star count:120.0

  1 project | /r/algoprojects | 10 Jun 2023

• api: NEW Data - star count:120.0

  1 project | /r/algoprojects | 9 Jun 2023
• A note from our sponsor - SaaSHub
  www.saashub.com | 11 Aug 2026

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