Python Blockchain

Open-source Python projects categorized as Blockchain

Top 23 Python Blockchain Projects

  1. chia-blockchain

    Chia blockchain python implementation (full node, farmer, harvester, timelord, and wallet)

  2. InfluxDB

    InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.

    InfluxDB logo
  3. lbry-sdk

    The LBRY SDK for building decentralized, censorship resistant, monetized digital content apps.

  4. mythril

    Mythril is a symbolic-execution-based securty analysis tool for EVM bytecode. It detects security vulnerabilities in smart contracts built for Ethereum and other EVM-compatible blockchains.

  5. manticore

    Symbolic execution tool

  6. rotki

    A portfolio tracking, analytics, accounting and management application that protects your privacy

  7. raiden

    Raiden Network

  8. SimpleCoin

    Just a really simple, insecure and incomplete implementation of a blockchain for a cryptocurrency made in Python as educational material. In other words, a simple Bitcoin clone. (by cosme12)

  9. SaaSHub

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    SaaSHub logo
  10. smart-contract-sanctuary

    πŸ¦πŸŒ΄πŸŒ΄πŸŒ΄πŸ¦• A home for ethereum smart contracts. 🏠

  11. solana-py

    Solana Python SDK

  12. smart-contracts

    Ethereum smart contracts for security and utility tokens

  13. bittensor

    Internet-scale Neural Networks

  14. bitcoin-abe

    Abe: block browser for Bitcoin and similar currencies

  15. 0xDeCA10B

    Sharing Updatable Models (SUM) on Blockchain

  16. defi

    Tools for use in DeFi. Impermanent Loss calculations, staking and farming strategies, coingecko and pancakeswap API queries, liquidity pools and more (by gauss314)

  17. yearn-vaults

    Yearn Vault smart contracts

  18. pool-reference

    Reference python implementation of Chia pool operations for pool operators

  19. QRL

    Quantum Resistant Ledger

  20. ecdsa-private-key-recovery

    A simple library to recover the private key of ECDSA and DSA signatures sharing the same nonce k and therefore having identical signature parameter r

  21. fabric-sdk-py

    Hyperledger Fabric Python SDK

  22. sepolia

    the sepolia/bepolia testnet configurations.

    Project mention: Run Sepolia node | dev.to | 2025-05-26
  23. py-stellar-base

    Stellar client library for the Python language

  24. machinaris

    An easy-to-use WebUI for crypto plotting and farming. Offers Bladebit, Gigahorse, MadMax, Chiadog and Plotman in a Docker container. Supports Chia, MMX, Chives, Flax, and HDDCoin among others.

  25. nft-generator-py

    This tool allows users to generate sets of unique images and metadata using weighted layer collections.

  26. SaaSHub

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    SaaSHub logo
NOTE: The open source projects on this list are ordered by number of github stars. The number of mentions indicates repo mentiontions in the last 12 Months or since we started tracking (Dec 2020).

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  • A note from our sponsor - InfluxDB
    www.influxdata.com | 24 Jun 2025
    InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now. Learn more β†’

Index

What are some of the best open-source Blockchain projects in Python? This list will help you:

# Project Stars
1 chia-blockchain 10,855
2 lbry-sdk 7,210
3 mythril 4,043
4 manticore 3,767
5 rotki 3,146
6 raiden 1,840
7 SimpleCoin 1,791
8 smart-contract-sanctuary 1,569
9 solana-py 1,367
10 smart-contracts 1,339
11 bittensor 1,168
12 bitcoin-abe 978
13 0xDeCA10B 581
14 defi 577
15 yearn-vaults 534
16 pool-reference 435
17 QRL 434
18 ecdsa-private-key-recovery 416
19 fabric-sdk-py 411
20 sepolia 387
21 py-stellar-base 366
22 machinaris 343
23 nft-generator-py 310

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