libBigWig
A C library for handling bigWig files (by dpryan79)
minimap2
A versatile pairwise aligner for genomic and spliced nucleotide sequences (by lh3)
libBigWig | minimap2 | |
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1 | 5 | |
71 | 1,696 | |
- | - | |
0.0 | 7.6 | |
almost 2 years ago | 13 days ago | |
C | C | |
MIT License | GNU General Public License v3.0 or later |
The number of mentions indicates the total number of mentions that we've tracked plus the number of user suggested alternatives.
Stars - the number of stars that a project has on GitHub. Growth - month over month growth in stars.
Activity is a relative number indicating how actively a project is being developed. Recent commits have higher weight than older ones.
For example, an activity of 9.0 indicates that a project is amongst the top 10% of the most actively developed projects that we are tracking.
Stars - the number of stars that a project has on GitHub. Growth - month over month growth in stars.
Activity is a relative number indicating how actively a project is being developed. Recent commits have higher weight than older ones.
For example, an activity of 9.0 indicates that a project is amongst the top 10% of the most actively developed projects that we are tracking.
libBigWig
Posts with mentions or reviews of libBigWig.
We have used some of these posts to build our list of alternatives
and similar projects. The last one was on 2021-09-16.
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Technical specification for the bigWig file format
And that is using libBigWig which specifically references Kent Utils.
minimap2
Posts with mentions or reviews of minimap2.
We have used some of these posts to build our list of alternatives
and similar projects. The last one was on 2023-11-06.
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Ask HN: Comment here about whatever you're passionate about at the moment
Interested as well! But the future is not so dark, things like e.g. https://github.com/lh3/minimap2 are a breath of fresh air.
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BLAST 10,000 genes?
No experience with this maybe try minimap2(https://github.com/lh3/minimap2) if this doesn't work fall back on blast/blat
- Truncating genome fastas to just overlapping regions
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Alignment of long reads to plasmid and generation of consensus sequence.
You can try minimap2 to align your long reads to your expected plasmid
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Questions about WGS mapping
It sounds like the mapping wasn't very good, you might want to try minimap2 as it is a newer algorithm.
What are some alternatives?
When comparing libBigWig and minimap2 you can also consider the following projects:
samtools - Tools (written in C using htslib) for manipulating next-generation sequencing data
bwa-mem2 - The next version of bwa-mem
bwa - Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment)
seqtk - Toolkit for processing sequences in FASTA/Q formats
bbi-js - Parser for bigwig and bigbed files
seqstats - Quick summary statistics on fasta/fastq(.gz) files
slivar - genetic variant expressions, annotation, and filtering for great good.
MethylDackel - A (mostly) universal methylation extractor for BS-seq experiments.
bwa-mem2 - The next version of bwa-mem
Klib - A standalone and lightweight C library
Bitgrid - Bitgrid - a new model of computation
biowasm - WebAssembly modules for genomics