bonito VS QEMU

There is a technology called Nanopore. I’ve never used it myself but the concept was to be able to sequence samples of nucleic acid out in the field. A quick pubmed search indicated that it can detect miRNA, but maybe with some modifications. https://nanoporetech.com Best of luck with it!

> An unpopular opinion: there are too many other logos that look like the original logo

There are also too many logos that look like the new logo. The first blue circle logos that spring to mind are Blue Circle Cement/Tarmac/Lafarge [1] and Oxford Nanopore [2].

[1]: https://en.wikipedia.org/wiki/Tarmac_(company)

[2]: https://nanoporetech.com/

Oxford Nanopore Technologies (https://nanoporetech.com/) | Front end developer | Full-time | Oxford | Remote (UK)

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and commercial presence in many global locations across the US, APAC and Europe. Our DNA/RNA sequencing platform is the only technology that offers real-time analysis (for rapid insights), in fully scalable formats from pocket to population scale. Our goal is to enable the analysis of any living thing, by anyone, anywhere.

Tech stack: Electron, Stencil, React, Typescript, RxJS, GRPC

For more details, please email: [email protected]

Ok this isn't really my area but I know that there are labs/companies performing these types of electrical current disturbance measurements of membrane-type proteins for both DNA sequencing (https://nanoporetech.com/) and protein sequencing (https://www.nature.com/articles/s41587-019-0401-y).

Now nanopore sequencing is solid state and gets much longer reads. https://nanoporetech.com/ and https://en.wikipedia.org/wiki/Nanopore_sequencing

Also best of luck with the basecaller, I will say that the latest guppy versions are very good, both in terms of accuracy and speed, as they are GPU accelerated and the best I've seen in accuracy. You may also be interested in Bonito, a tool to generate your own GPU basecalling model or tweak existing models to your data. https://github.com/nanoporetech/bonito.

My most-wanted QEMU feature: https://github.com/qemu/qemu/commit/a2260983c6553

Using `gic-version=3` on macOS you can now use more than 8 cores on ARM chips.

A better solution is just to write a plain ass shell script that tests if various C snippets compile.

https://github.com/oilshell/oil/blob/master/configure

https://github.com/oilshell/oil/blob/master/build/detect-pwe...

Not an unholy mix of m4, shell, and C, all in the same file.

---

These are the same style as a the configure scripts that Fabrice Bellard wrote for tcc and QEMU.

They are plain ass shell scripts, because he actually understands the code he writes.

https://github.com/qemu/qemu/blob/master/configure

https://github.com/TinyCC/tinycc/blob/mob/configure

OCaml’s configure script is also “normal”.

You don’t have to copy and paste thousands of lines of GNU stuff that you don’t understand.

(copy of lobste.rs comment)

Related:

A fast Pascal (Delphi) WebAssembly interpreter:

https://github.com/marat1961/wasm

WASM-4:

https://github.com/aduros/wasm4

Curated list of awesome things regarding WebAssembly (wasm) ecosystem:

https://github.com/mbasso/awesome-wasm

Also, it would be nice if there was a WASM (soft) CPU for QEMU, which (if it existed!) would go here:

https://github.com/qemu/qemu/tree/master/target

> architectural registers are always updated

In tiny code, the guest registers (global TCG variables) are stored in the host's registers until you either call an helper which can access the CPU state or you return (`git grep la_global_sync`). This is the reason why QEMU is not so terribly slow.

But after a check, this also happens when you access the guest memory address space! https://github.com/qemu/qemu/blob/master/include/tcg/tcg-opc... (TCG_OPF_SIDE_EFFECTS is what matters)

But still, in the end, it's the same problem. What QEMU does, can be done in LLVM too. You could probably be more efficient in LLVM by using the exception handling mechanism (invoke and friends) to only serialize back to memory when there's an actual exception, at the cost of higher register pressure. More or less what we do here: https://rev.ng/downloads/bar-2019-paper.pdf

Um, in case you don't know, UTM (based on QEMU) is out for quite a while.

Some of these tools include Oracle VM VirtualBox (that I've used since before the acquisition of Sun Microsystems by Oracle), VMWare Workstation Player, and QEMU, but last year, I found out about Multipass.

For C/C++ projects that use meson as the build system, there is an excellent way to manage dependencies:

https://mesonbuild.com/Wrapdb-projects.html

https://mesonbuild.com/Wrap-dependency-system-manual.html

meson will download and build the libraries automatically and give you a variable which you pass as a regular dependency into the built target:

https://github.com/qemu/qemu/tree/005ad32358f12fe9313a4a0191...

https://github.com/harfbuzz/harfbuzz/tree/main/subprojects

https://github.com/harfbuzz/harfbuzz/blob/37457412b3212463c5...

Or, if you're using proper operating systems, they're managed by the usual package manager, just like everything else.

For all the users of the Linux platform, QEMU is the VM that you should go for. This software comes without any price tag and works as an emulator of various machines with utmost ease and completion; the software uses dynamic translations to emulate hardware peripherals and enhances its overall performance. If you are using QEMU as a virtualizer, then it will function exactly like the host system (provided you have the right set of hardware).

In this tutorial, we set up macOS and Windows virtual machines on UTM, a macOS application that provides a GUI wrapper for QEMU, a powerful open-source emulator and virtualizer. UTM allows you to easily manage and run virtual machines without memorizing complex commands. It also has special handling for macOS, making it simpler to install compared to other virtual machine software.