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DolphinDOS2
DolphinDOS 2 is a kernal ROM replacement for the C64 and 1541 disk drive to speed up disk operations.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
This is very easy to find out. I just did. It took me less than a minute to figure the answer out. All you have to do is look here: https://github.com/MiSTer-devel/C64_MiSTer
I have both a MiSTer and an Ultimate64 and even though the MiSTer is getting better, the U64 is much more compatible with any d64 or g64 I throw at it. It also can use dolphindos to load disk images faster than jiffydos.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.