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Top 23 Python ai-agent Projects
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crewAI
Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.
GitHub - crewAIInc/crewAI
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InfluxDB
InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
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deer-flow
DeerFlow is a community-driven Deep Research framework, combining language models with tools like web search, crawling, and Python execution, while contributing back to the open-source community.
View the Project on GitHub
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lastmile-ai/mcp-agent
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agent-squad
Flexible and powerful framework for managing multiple AI agents and handling complex conversations
Project mention: Orchestrating Multi-Agents: Unifying Fragmented Tools into Coordinated Workflows | dev.to | 2025-06-29AWS Agent Squad (GitHub)
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Project mention: Show HN: Agent S: an open agentic framework that uses computers | news.ycombinator.com | 2025-05-01
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Sevalla
Deploy and host your apps and databases, now with $50 credit! Sevalla is the PaaS you have been looking for! Advanced deployment pipelines, usage-based pricing, preview apps, templates, human support by developers, and much more!
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PraisonAI
PraisonAI is a production-ready Multi AI Agents framework, designed to create AI Agents to automate and solve problems ranging from simple tasks to complex challenges. It provides a low-code solution to streamline the building and management of multi-agent LLM systems, emphasising simplicity, customisation, and effective human-agent collaboration.
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Project mention: Introducing Potpie's Slack Integration: Bring Your Custom AI Agents to Where You Work | dev.to | 2025-04-24
Potpie is an open-source platform that allows you to build and deploy custom AI agents tailored to your specific codebase. These agents can handle a wide range of tasks including debugging, code reviewing, code generation, onboarding, etc.
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aci
ACI.dev is the open source tool-calling platform that hooks up 600+ tools into any agentic IDE or custom AI agent through direct function calling or a unified MCP server. The birthplace of VibeOps.
Project mention: Ask HN: Is manually discovering and configuring MCP servers the only way? | news.ycombinator.com | 2025-08-01 -
gptme
Your agent in your terminal, equipped with local tools: writes code, uses the terminal, browses the web, vision.
Project mention: Gptme v0.27 released – general purpose agent in your terminal | news.ycombinator.com | 2025-03-11 -
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agentUniverse
agentUniverse is a LLM multi-agent framework that allows developers to easily build multi-agent applications.
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OpenAdapt
Open Source Generative Process Automation (i.e. Generative RPA). AI-First Process Automation with Large ([Language (LLMs) / Action (LAMs) / Multimodal (LMMs)] / Visual Language (VLMs)) Models
Project mention: FastVLM: Dramatically Faster Vision Language Model from Apple | news.ycombinator.com | 2025-05-12 -
Project mention: Lessons Learned Building MCP for Video Infrastructure Startup | news.ycombinator.com | 2025-04-10
Presenting users with numerous tools can overwhelm and complicate testing. We learned it's far better to offer one intelligent, context-aware interface (e.g., VideoDB Director), managing tool selection and reasoning internally. (open source link here — https://github.com/video-db/Director)
3. Remote Servers Improve Everything
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Project mention: Show HN: Blast – Fast, multi-threaded serving engine for web browsing AI agents | news.ycombinator.com | 2025-05-02
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trustgraph
The Next Generation AI Product Creation Platform. Complete context engineering and LLM orchestration with APIs or private deployments. Run anywhere - local, cloud, or bare metal.
Project mention: Stop Thinking AI Agents, Start Engineering Autonomous Knowledge Operations | dev.to | 2025-04-09This is precisely the philosophy behind TrustGraph. We realized that the conversation needed to evolve beyond just the agent itself to encompass the entire knowledge-driven system. TrustGraph is an Autonomous Knowledge Operations Platform designed to provide the foundational elements missing from simple agent frameworks:
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Project mention: Recursive Planning Based Open Writing Project: WriteHERE | news.ycombinator.com | 2025-05-05
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Project mention: How to create a digital twin of yourself that joins low-value meetings for you | dev.to | 2025-07-21
So, now you only need to worry about how I could get the agent into a video conference. Enter joinly, an open-source project I'm currently working on with two friends: It is a connector middleware specifically designed to enable AI agents to actively participate in video calls. How does it work? Ultimately, joinly is also just an MCP server that you can host yourself, providing your agent with essential meeting tools (such as speak_text and send_chat_message) alongside automatic real-time transcription.
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SaaSHub
SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives
NOTE:
The open source projects on this list are ordered by number of github stars.
The number of mentions indicates repo mentiontions in the last 12 Months or
since we started tracking (Dec 2020).
Python ai-agents discussion
Python ai-agents related posts
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🤖 Build Your First Fully Autonomous AI Agent - Free Workshop! 🚀
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Building PoC Agents in Minutes
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The Agent Paradox: Why AI Agents Shine in Demos But Stumble in Production
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So You Want to Build an Open Source Alternative to ChatGPT for Teams
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Jepsen‑style chaos CI before clustering
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Show HN: AgentState – Lightweight state manager for multi-agent AI workflows
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Show HN: Weam – open-source AI platform for teams
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A note from our sponsor - InfluxDB
www.influxdata.com | 1 Sep 2025
Index
What are some of the best open-source ai-agent projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | crewAI | 36,133 |
| 2 | deer-flow | 16,691 |
| 3 | parlant | 8,189 |
| 4 | mcp-agent | 7,151 |
| 5 | cognee | 6,867 |
| 6 | agent-squad | 6,417 |
| 7 | Agent-S | 6,199 |
| 8 | TaskWeaver | 5,881 |
| 9 | PraisonAI | 5,323 |
| 10 | potpie | 4,918 |
| 11 | aci | 4,587 |
| 12 | gptme | 3,980 |
| 13 | readme-ai | 2,442 |
| 14 | memU | 1,893 |
| 15 | agentUniverse | 1,615 |
| 16 | functionary | 1,577 |
| 17 | OpenAdapt | 1,365 |
| 18 | Director | 1,050 |
| 19 | agents | 580 |
| 20 | blast | 547 |
| 21 | trustgraph | 540 |
| 22 | WriteHERE | 352 |
| 23 | joinly | 335 |
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InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
www.influxdata.com