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Top 23 Python ai-agent Projects
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crewAI
Framework for orchestrating role-playing, autonomous AI agents. By fostering collaborative intelligence, CrewAI empowers agents to work together seamlessly, tackling complex tasks.
Project mention: CrewAI: Framework for orchestrating role-playing, autonomous AI agents | news.ycombinator.com | 2025-05-08 -
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agent-squad
Flexible and powerful framework for managing multiple AI agents and handling complex conversations
Project mention: Orchestrating Multi-Agents: Unifying Fragmented Tools into Coordinated Workflows | dev.to | 2025-06-29AWS Agent Squad (GitHub)
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That’s exactly what MCP Agent is built for.
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cognee - memory tool for AI apps and Agents | Remote and Berlin | Full time | 100k EUR
At cognee we are working on building graph/vector based memory on top of vector and graph stores. Our pipelines had 116k runs last month and we are projecting north of a million in a few months. We need help on the infra side.
Check our OSS tool here: https://github.com/topoteretes/cognee
Open Roles: Platform Engineer - https://apply.workable.com/topoteretes-ug-haftungsbeschrankt...
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Project mention: Show HN: Agent S: an open agentic framework that uses computers | news.ycombinator.com | 2025-05-01
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Project mention: Why Generative AI Coding Tools and Agents Do Not Work For ME | news.ycombinator.com | 2025-06-16
3. https://github.com/julep-ai/julep/blob/dev/AGENTS.md:
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InfluxDB
InfluxDB – Built for High-Performance Time Series Workloads. InfluxDB 3 OSS is now GA. Transform, enrich, and act on time series data directly in the database. Automate critical tasks and eliminate the need to move data externally. Download now.
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Project mention: Introducing Potpie's Slack Integration: Bring Your Custom AI Agents to Where You Work | dev.to | 2025-04-24
Potpie is an open-source platform that allows you to build and deploy custom AI agents tailored to your specific codebase. These agents can handle a wide range of tasks including debugging, code reviewing, code generation, onboarding, etc.
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aci
ACI.dev is the open source platform for VibeOps and infrastructure that connects your AI agents to 600+ tool integrations with multi-tenant auth, granular permissions, and access through direct function calling or a unified MCP server.
Project mention: Data fetching in '/apps/[appName]' route in open source ACI.dev platform. | dev.to | 2025-05-08page.tsx- file
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gptme
Your agent in your terminal, equipped with local tools: writes code, uses the terminal, browses the web, vision.
Project mention: Gptme v0.27 released – general purpose agent in your terminal | news.ycombinator.com | 2025-03-11 -
parlant
The open-source backbone for LLM agents that stay under control as you scale their complexity.
⚡️ https://github.com/emcie-co/parlant
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agentUniverse
agentUniverse is a LLM multi-agent framework that allows developers to easily build multi-agent applications.
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OpenAdapt
Open Source Generative Process Automation (i.e. Generative RPA). AI-First Process Automation with Large ([Language (LLMs) / Action (LAMs) / Multimodal (LMMs)] / Visual Language (VLMs)) Models
Project mention: FastVLM: Dramatically Faster Vision Language Model from Apple | news.ycombinator.com | 2025-05-12 -
Project mention: Lessons Learned Building MCP for Video Infrastructure Startup | news.ycombinator.com | 2025-04-10
Presenting users with numerous tools can overwhelm and complicate testing. We learned it's far better to offer one intelligent, context-aware interface (e.g., VideoDB Director), managing tool selection and reasoning internally. (open source link here — https://github.com/video-db/Director)
3. Remote Servers Improve Everything
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Project mention: Show HN: Blast – Fast, multi-threaded serving engine for web browsing AI agents | news.ycombinator.com | 2025-05-02
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trustgraph
Take control of your data and AI future. Connect LLMs to graph driven intelligence automatically built from your data. Build, deploy, and manage anywhere from local, cloud, or on-prem.
Project mention: Stop Thinking AI Agents, Start Engineering Autonomous Knowledge Operations | dev.to | 2025-04-09This is precisely the philosophy behind TrustGraph. We realized that the conversation needed to evolve beyond just the agent itself to encompass the entire knowledge-driven system. TrustGraph is an Autonomous Knowledge Operations Platform designed to provide the foundational elements missing from simple agent frameworks:
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Project mention: Recursive Planning Based Open Writing Project: WriteHERE | news.ycombinator.com | 2025-05-05
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Project mention: Designing Pareto-optimal RAG workflows with syftr | news.ycombinator.com | 2025-05-28
https://github.com/datarobot/syftr/blob/main/docs/datasets.m...
You need custom QA pairs for custom scenarios.
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Agent-Wiz
A CLI tool for threat modeling and visualizing AI agents built using popular frameworks like LangGraph, AutoGen, CrewAI, and more.
Project mention: Show HN: A CLI tool to visualize and threat model AI Agents | news.ycombinator.com | 2025-04-23 -
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Project mention: The Open-Source AI Co-Scientist Making ML More Accessible for Your Research | news.ycombinator.com | 2025-05-28
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NOTE:
The open source projects on this list are ordered by number of github stars.
The number of mentions indicates repo mentiontions in the last 12 Months or
since we started tracking (Dec 2020).
Python ai-agents discussion
Python ai-agents related posts
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🛠️ From LLM to Action Agent: How We Gave ChatGPT Superpowers with ToolAgent (MultiMindSDK)
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💡 Use FederatedRouter to Switch Between GPT-4, Gemini, and Mistral in One AI Agent (Open Source)
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Show HN: Kanban-Board agent management for software dev agents, open source
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Show HN: MCP server built around the ipython shell
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Show HN: Open Operator Evals – real-world benchmarks for LLM web agents
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Show HN: I built an AI agent for a mobile robot
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Show HN: I built an LLM security tool that broke OpenAI and Claude models
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Index
What are some of the best open-source ai-agent projects in Python? This list will help you:
| # | Project | Stars |
|---|---|---|
| 1 | crewAI | 33,621 |
| 2 | agent-squad | 6,098 |
| 3 | mcp-agent | 6,094 |
| 4 | cognee | 6,127 |
| 5 | TaskWeaver | 5,794 |
| 6 | Agent-S | 5,690 |
| 7 | julep | 5,603 |
| 8 | potpie | 4,680 |
| 9 | aci | 4,173 |
| 10 | gptme | 3,887 |
| 11 | parlant | 3,208 |
| 12 | readme-ai | 2,223 |
| 13 | agentUniverse | 1,515 |
| 14 | OpenAdapt | 1,314 |
| 15 | Director | 952 |
| 16 | blast | 528 |
| 17 | trustgraph | 470 |
| 18 | agents | 459 |
| 19 | WriteHERE | 334 |
| 20 | syftr | 279 |
| 21 | Agent-Wiz | 214 |
| 22 | graphsignal-python | 204 |
| 23 | Curie | 192 |
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