edlib VS casadi

I’ve got a similar situation. I was implementing the Smith-Waterman algorithm when I figured someone had to have already written a “fast” version of this. I found the edlib package (https://github.com/Martinsos/edlib) which does sequence alignment using Levenshtein distance. Essentially same DP algorithm as your traditional NW or SW only this is a C++ implementation with a Python wrapper. (I’m assuming you’re using Python, could be wrong though). The pertinent aspects of the output of this function contains the distance (dissimilarity) and the location (what index does the alignment start and end). This tool may go a ways to helping your pipeline. You could also look to metagenomic papers for inspiration as this is a problem (find a substring in a huge amount of data) that the community contends with all the time. Kmer based approach may also be useful if you want to attempt the alignment free path. Cheers.

I appear to get that error with the original source as well. https://github.com/Martinsos/edlib

Interface for several solvers and integrators.

Howdy! Collocation methods can be... tricky. For NMPC control of vehicles, success has been had using direct multiple shooting. Also easier to implement and more intuitive. In fact, this example from the GH is pretty instructive: https://github.com/casadi/casadi/blob/master/docs/examples/python/race_car.py

JuMP.jl (Julia) or casADi (Python) are good choices.

Python is not mature in this area. If you ask Google what Simulink for Python is, you get responses that point to dead libraries that were never feature complete and slow. The absolute closest is CASADI which is nice for some things but doesn't even have a true causal modeling interface and is mostly abandoned by the developers (they put a patch in every now and then, but just look at the commit graph), and it's slow compared to the Julia tools, so much so that PyBAMM is interfacing with ModelingToolkit.jl in Julia for a performance boost. Python is not the place to be for causal/acausal modeling or controls. Anyone who is saying "Python is mature" here is saying it in the abstract and not in the context of your actual question. Yes, Python has web development frameworks. No it does not have good libraries for tons of areas (control, acausal modeling, pharmacometrics, etc.).