bcolz VS Numba

What you need for your use case is a column-oriented store. I recommend explore bcolz or apache arrow for a column file-based systems. These are very fast, support memory mapping, uses compression and SSD speed (and even CPU architecture, in case of arrow) optimally almost out of the box, and has good interfaces to Numpy and Pandas (in case you are using Python for final data consumption and analysis). The columnar structure makes it easy to add or delete a column easily (or even dynamically). If you need a more scalable (albeit at the cost of speed) solution, you can devise a schema over a regular columnar db or an nosql db - see arctic from Man group for an example.

Around the same time, I discovered Numba and was fascinated by how easily it could bring huge performance improvements to Python code.

Simulations are, at least in my experience, numba’s [0] wheelhouse.

[0]: https://numba.pydata.org/

That's very cool. Numba introduces just-in-time compilation to Python via decorators and its sole reason for being is to turn everything it can into abstract syntax trees.

A super-fast backtesting engine built in NumPy and accelerated with Numba.

Regarding speed, I don't agree this is a good argument against Python. For example, it seems no one here has yet mentioned numba, a Python JIT compiler. With a simple decorator you can compile a function to machine code with speeds on par with C. Numba also allows you to easily write cuda kernels for GPU computation. I've never had to drop down to writing C or C++ to write fast and performant Python code that does computationally demanding tasks thanks to numba.

Just for reference,

* Nuitka[0] "is a Python compiler written in Python. It's fully compatible with Python 2.6, 2.7, 3.4, 3.5, 3.6, 3.7, 3.8, 3.9, 3.10, and 3.11."

* Pypy[1] "is a replacement for CPython" with builtin optimizations such as on the fly JIT compiles.

* Cython[2] "is an optimising static compiler for both the Python programming language and the extended Cython programming language... makes writing C extensions for Python as easy as Python itself."

* Numba[3] "is an open source JIT compiler that translates a subset of Python and NumPy code into fast machine code."

* Pyston[4] "is a performance-optimizing JIT for Python, and is drop-in compatible with ... CPython 3.8.12"

[0] https://github.com/Nuitka/Nuitka

[1] https://www.pypy.org/

[2] https://cython.org/

[3] https://numba.pydata.org/

[4] https://github.com/pyston/pyston

For the benefit of future readers: https://numba.pydata.org/

Taichi (similar to numba) is a python library that allows you to write high speed code within python. So your program consists of slow python that gets interpreted regularly, and fast python (fully type annotated and restricted to a subset of the language) that gets parallellized and jitted for CPU or GPU. And you can mix the two within the same source file.