infercnv

Inferring CNV from Single-Cell RNA-Seq (by broadinstitute)
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  • How reliable are CNV calling methods from single cell RNAseq?
    1 project | /r/bioinformatics | 14 Apr 2022
    you can predict copy number based on elevated gene expression. this idea is implemented in tools such as infercnv. In my experience you can get away with using guaranteed normal such as immune cells as your diploid reference. However also in my case I have matched CNV from bulk data to corroborate.

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broadinstitute/infercnv is an open source project licensed under GNU General Public License v3.0 or later which is an OSI approved license.

The primary programming language of infercnv is R.


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