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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Regarding Python's dependency management and virtual env, yeah it sucks. But to solve those issues look into Poetry (https://python-poetry.org/). I got introduced to it at my last org and it is a must have for any Python project for me now. Makes the dependency management in Python so much better.
Now I don't want to scare anyone here, but have you tried TypeScript? I have my own note-taking solution with a bunch of personal scripts and I write them all in TS on Deno runtime. It's nice because installing it is super easy, unlike Node.js, it borrows a lot of ideas from Go and is super secure, so you can ensure your installed packages don't do unexpected things and it supports TypeScript natively.