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BOLT
Discontinued Binary Optimization and Layout Tool - A linux command-line utility used for optimizing performance of binaries (by facebookarchive)
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
I was also very curious about this after doing some quick reading up on sccache, so I checked the GitHub actions for the main rust repo. Looks like they already use sccache. https://github.com/rust-lang/rust/blob/master/.github/workflows/ci.yml
Google automatically profiles everything running in their datacenters and compiles everything with LTO+PGO on by default. And beyond LTO, both Facebook's BOLT and Google's Propeller can perform additional binary optimizations on top of what regular LTO does.