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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Used to great effect by fuckit.py
Isn't Django written in pure Python, and from what I know Django is pretty fast and scalable.
All the network handling for Instagram and all other Meta apps on all platforms is handled by their own C++ library https://github.com/facebookexperimental/libunifex.
NOTE:
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Hence, a higher number means a more popular project.