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pypath
Python module for prior knowledge integration. Builds databases of signaling pathways, enzyme-substrate interactions, complexes, annotations and intercellular communication roles.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
If you are just looking for edgelists of any kind you can download them from a number of resources, like OmniPath (https://omnipathdb.org/). You can query data a lot of ways, through python, R, read them directly into Cytoscape, or use the webservice (https://github.com/saezlab/pypath/blob/master/webservice.rst) like the following example, where the first two columns contain the source and target nodes: