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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
There might be, the code is open source (https://github.com/BackofenLab/IntaRNA/) so just download it, and run it through a code profiler, see where most of the runtime is spend and optimise the code.
NOTE:
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Hence, a higher number means a more popular project.