Top 14 Python automatic-differentiation Projects

automatic-differentiation

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1. autograd

   1 6 7,539 8.1 Python

   Efficiently computes derivatives of NumPy code.

   

2. AppSignal

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3. pennylane

   2 11 3,489 9.9 Python

   PennyLane is an open-source quantum software platform for quantum computing, quantum machine learning, and quantum chemistry. Create meaningful quantum algorithms, from inspiration to implementation.

   

   Project mention: AWS Summit Bogotá 2026: Paradigmas agénticos, resiliencia multirregión y seguridad declarativa | dev.to | 2026-08-05

4. JAXFLUIDS

   3 1 653 7.6 Python

   Differentiable Fluid Dynamics Package

   

5. torchopt

   4 1 638 0.0 Python

   TorchOpt is an efficient library for differentiable optimization built upon PyTorch.

   

6. catalyst

   5 2 238 9.8 Python

   A JIT compiler for hybrid quantum programs in PennyLane (by PennyLaneAI)

   

   Project mention: PennyLane is an open-source quantum software platform for quantum | news.ycombinator.com | 2026-07-17

   For those interested in compilers/LLVM/MLIR, the underlying compiler (Catalyst) may also be interesting: https://github.com/pennylaneai/catalyst

7. neograd

   6 2 236 0.0 Python

   A deep learning framework created from scratch with Python and NumPy

   

8. torchquad

   7 1 229 8.4 Python

   Numerical integration in arbitrary dimensions on the GPU using PyTorch / TF / JAX

   

9. SaaSHub

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10. tesseract-core

    8 2 135 9.4 Python

    Universal components for differentiable scientific computing. :package:

    

    Project mention: Tesseract Core: Universal components for differentiable scientific computing | news.ycombinator.com | 2026-07-16

11. tensorcircuit-ng

    9 5 92 9.6 Python

    Next-gen AI-native tensor-network-based quantum software framework

    

    Project mention: TensorCircuit-NG vs cuQuantum on H200: JIT compilation beats the "magic GPU library" assumption | dev.to | 2026-06-06

    We used the workload as in the script for 1D TFIM VQE task:

12. tensortrax

    10 1 11 6.9 Python

    Differentiable Tensors based on NumPy Arrays

    

13. advect

    11 1 9 8.5 Python

    Automatic differentiation for the NumPy code you already write

    

    Project mention: Show HN: Advect – autodiff for NumPy and Array API programs | news.ycombinator.com | 2026-08-11

    I built Advect, an automatic differentiation library for scientific Python. It provides broad NumPy API coverage, follows the Python Array API standard, and works with ordinary Python functions.

    In addition to dynamic differentiation, Advect can stage a function into a reusable program that can be optimized, differentiated again, serialized, and loaded later. There is also some support for SciPy, xarray, and interoperability with other autodiff frameworks.

    The linked playground runs entirely in the browser through Pyodide, so you can try tracing and differentiating an expression without installing anything.

    The first public release is available with pip install advect.

    Source: https://github.com/yaugenst/advect

14. slope-ad

    12 1 7 9.6 Python

    A small automatic differentiation engine, supporting higher-order derivatives

    

15. memoized_coduals

    13 2 3 2.6 Python

    Shows that it is possible to implement reverse mode autodiff using a variation on the dual numbers called the codual numbers

    

16. adiabatic-silicon-aging-guard

    14 1 1 7.9 Python

    Experimental 3-tier silicon failure-fencing engine isolating volatile NaN/Inf bleeding via runtime CPython method table interception and timing-frozen JAX shard_map topologies.

    

    Project mention: Show HN: Overcoming silicon-level aging through fault tolerance (PoC) | news.ycombinator.com | 2026-08-19

17. SaaSHub

    www.saashub.com sponsored

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    

Python automatic-differentiation related posts

• AWS Summit Bogotá 2026: Paradigmas agénticos, resiliencia multirregión y seguridad declarativa

  3 projects | dev.to | 5 Aug 2026

• PennyLane is an open-source quantum software platform for quantum

  3 projects | news.ycombinator.com | 17 Jul 2026

• Tesseract Core: Universal components for differentiable scientific computing

  1 project | news.ycombinator.com | 16 Jul 2026

• List of free Quantum Toolkits

  4 projects | dev.to | 10 Dec 2024

• LLMs on your local Computer (Part 1)

  7 projects | dev.to | 11 Mar 2024

• Show HN: Elodin – A better framework for physics simulation

  6 projects | news.ycombinator.com | 6 Mar 2024

• Trade-Offs in Automatic Differentiation: TensorFlow, PyTorch, Jax, and Julia

  7 projects | news.ycombinator.com | 25 Dec 2021
• A note from our sponsor - SaaSHub
  www.saashub.com | 13 Oct 2026

  SaaSHub helps you find the best software and product alternatives Learn more →

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