Top 23 Python Agent Projects

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1. ragflow

   1 18 82,474 10.0 Python

   RAGFlow is a leading open-source Retrieval-Augmented Generation (RAG) engine that fuses cutting-edge RAG with Agent capabilities to create a superior context layer for LLMs

   

   Project mention: I Scanned 5 Popular Open-Source AI Projects for EU AI Act Compliance. Here's What I Found. | dev.to | 2026-03-31

   I ran AIR Blackbox (the scanner itself), Browser Use (79K+ stars), RAGFlow (76K+ stars), LiteLLM (23K+ stars), and Superlinked (15K+ stars) through the same compliance checks.

2. SaaSHub

   www.saashub.com featured

   SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

   

3. OpenHands

   2 42 76,575 10.0 Python

   🙌 OpenHands: AI-Driven Development

   

   Project mention: Agent-Ready Engineering Infrastructure | dev.to | 2026-05-05

   OpenHands AGENTS.md

4. LlamaFactory

   3 8 72,081 9.6 Python

   Unified Efficient Fine-Tuning of 100+ LLMs & VLMs (ACL 2024)

   

   Project mention: Llama-Factory: Unified, Efficient Fine-Tuning for 100 Open LLMs | news.ycombinator.com | 2025-09-18

5. deer-flow

   4 16 70,969 9.9 Python

   An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.

   

   Project mention: The AI Engineering Baseline | dev.to | 2026-06-08

   Tools have been trending in this direction for the last 3-6 months with features like "Assign to Copilot" in GitHub.com, and the Linear's work tracking system where its unique sales pitch is "write tickets for agents to work on here". The final form of this kind of solution is currently a vague, but there are several projects already pitching to own this space such as Open AI's Symphony project (https://openai.com/index/open-source-codex-orchestration-symphony/), ByteDance's DeerFlow (https://github.com/bytedance/deer-flow) which pitches itself as "an open-source super-agent harness", and other similar projects.

6. MetaGPT

   5 39 68,683 9.1 Python

   🌟 The Multi-Agent Framework: First AI Software Company, Towards Natural Language Programming

   

   Project mention: Backlog.md – CLI that auto-generates task files (took my Claude success to 95 %) | news.ycombinator.com | 2025-07-06

7. unsloth

   6 34 66,397 10.0 Python

   Unsloth Studio is a web UI for training and running open models like Gemma 4, Qwen3.6, DeepSeek, gpt-oss locally.

   

   Project mention: I Trained an LLM on 75K of My Own Messages So It Would Stop Writing Like a Chatbot | dev.to | 2026-05-08

   Training: unsloth + trl (SFTTrainer). Unsloth handles the 4-bit quantization and gradient checkpointing; trl handles the training loop.

8. learn-claude-code

   7 4 66,285 5.8 Python

   Bash is all you need - A nano claude code–like 「agent harness」, built from 0 to 1

   

   Project mention: 🤖 Learn Harness Engineering by Building a Mini Claude Code 💻 | dev.to | 2026-04-21

   Note: This is a fork of shareAI-lab/learn-claude-code with all agents migrated from the Anthropic SDK to the OpenAI SDK (openai Python package). All agents work with any OpenAI-compatible endpoint — cloud APIs (OpenAI, GitHub Models, Azure OpenAI) or local servers (LM Studio, Ollama, GPT4All).

9. mem0

   8 29 58,292 9.6 Python

   Universal memory layer for AI Agents

   

   Project mention: AI Builder Notes - Week of June 8, 2026 | dev.to | 2026-06-08

   Agents need to compress work into state. [10] Mem0 positions memory inside the harness alongside tools and coordination. [11] [17]

10. ChatTTS

    9 4 39,435 6.2 Python

    A generative speech model for daily dialogue.

    

11. khoj

    10 53 35,097 9.7 Python

    Your AI second brain. Self-hostable. Get answers from the web or your docs. Build custom agents, schedule automations, do deep research. Turn any online or local LLM into your personal, autonomous AI (gpt, claude, gemini, llama, qwen, mistral). Get started - free.

    

    Project mention: 25 Trending Self-Hosted Projects on GitHub | dev.to | 2026-04-02

12. AstrBot

    11 2 34,454 9.9 Python

    AI Agent Assistant & development framework that integrates lots of IM platforms, LLMs, plugins and AI feature, and can be your openclaw alternative. ✨

    

13. gpt-researcher

    12 8 27,645 9.4 Python

    An autonomous agent that conducts deep research on any data using any LLM providers

    

    Project mention: 1500 Lines of Markdown vs 15000 Lines of Python. | dev.to | 2025-12-31

    I spent a weekend studying GPT-Researcher, an open-source project with 24,000+ GitHub stars. It builds an autonomous research agent that generates comprehensive reports with citations. The architecture is elegant: multiple specialized agents coordinate through LangGraph, parallel execution speeds up research, and quality gates ensure reliable output.

14. agentscope

    13 4 26,737 9.6 Python

    Build and run agents you can see, understand and trust.

    

    Project mention: All Data and AI Weekly #207: 15 Sept 2025 | dev.to | 2025-09-15

    GitHub Link: https://github.com/agentscope-ai/agentscope Summary: Agentscope is an agent-oriented programming library that makes it easier to build LLM applications. It's designed to be "developer-centric" with features like asynchronous execution, parallel tool calls, and real-time steering. It offers a transparent approach where prompt engineering and API invocation are fully visible and controllable. Why it's important: Agentscope, along with its related libraries like agentscope-runtime and agentscope-studio, provides a comprehensive toolkit for not only developing but also deploying and visualizing agent-based applications.

15. OpenViking

    14 3 25,521 9.8 Python

    OpenViking is an open-source context database designed specifically for AI Agents(such as openclaw). OpenViking unifies the management of context (memory, resources, and skills) that Agents need through a file system paradigm, enabling hierarchical context delivery and self-evolving.

    

    Project mention: ما هو أوبن فايكنج؟ شرح شامل ومبسط | dev.to | 2026-03-19

16. serena

    15 17 25,296 9.9 Python

    A powerful MCP toolkit for coding, providing semantic retrieval and editing capabilities - the IDE for your agent

    

    Project mention: Ask HN: SoTA of Context Building Methods | news.ycombinator.com | 2026-04-06

    You should add Serena https://github.com/oraios/serena to your list.

    Serena gives you symbol-level navigation, reading, and editing via tree-sitter. So you're already getting much of what CoderLM offers — plus Serena has editing capabilities(replace symbol body, insert before/after symbol, rename). GitNexus goes further with the graph/impact analysis layer on top.

    I personally use Serena and GitNexus.

    The case for using both

      - GitNexus tells you what to change (impact analysis, dependency maps, blast radius)

17. adk-python

    16 58 20,085 9.9 Python

    An open-source, code-first Python toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.

    

    Project mention: Google ADK CLI: The Fastest Way to Build and Ship AI Agents in 2026 [Guide] | dev.to | 2026-06-11

    First, ADK is genuinely multi-model. It supports Gemini, Gemma, Claude (via Vertex), Ollama, vLLM, LiteLLM, and LiteRT-LM. You're not locked into Gemini. You can route different agent tasks to different models based on cost, latency, or capability. This matters in production, where your summarization agent absolutely doesn't need the same model as your code generation agent.

18. owl

    17 11 19,842 8.3 Python

    🦉 OWL: Optimized Workforce Learning for General Multi-Agent Assistance in Real-World Task Automation

    

    Project mention: Launch: Eigent – Open-Source Local-First Multi-Agent Workforce Built on Camel-AI | news.ycombinator.com | 2025-07-30

    We built on top of our previous project OWL which ranked top 1 on GAIA: https://github.com/camel-ai/owl in March. For the Eigent update, we haven't got to benchmark it on GAIA yet. Will do it soon in the up coming weeks. Sorry for the confusion.

19. SWE-agent

    18 10 19,487 8.1 Python

    SWE-agent takes a GitHub issue and tries to automatically fix it, using your LM of choice. It can also be employed for offensive cybersecurity or competitive coding challenges. [NeurIPS 2024]

    

    Project mention: Boost Your Coding Agent and Understand Its Reasoning with 3 Simple Prompts | dev.to | 2025-06-20

    SWE-Agent

20. DeepResearch

    19 5 19,369 9.3 Python

    Tongyi Deep Research, the Leading Open-source Deep Research Agent

    

    Project mention: Tongyi DeepResearch – open-source 30B MoE Model that rivals OpenAI DeepResearch | news.ycombinator.com | 2025-11-02

21. agent-zero

    20 5 18,033 9.9 Python

    Agent Zero AI framework

    

    Project mention: OSS Alternative to Open WebUI – ChatGPT-Like UI, API and CLI | news.ycombinator.com | 2025-11-03

22. agent-lightning

    21 3 17,301 9.4 Python

    The absolute trainer to light up AI agents.

    

    Project mention: Daily Artificial Intelligence Digest - Oct 26, 2025 | dev.to | 2025-10-25

    Microsoft's agent-lightning project offers a comprehensive toolkit aimed at accelerating the process of building, testing, and deploying AI Agents. This open-source initiative highlights the industry's commitment to enabling faster development and implementation of advanced AI capabilities, providing developers with robust resources to streamline AI agent creation.

23. camel

    22 18 17,169 9.9 Python

    🐫 CAMEL: The first and the best multi-agent framework. Finding the Scaling Law of Agents. https://www.camel-ai.org

    

    Project mention: Eigent: An open source Claude cowork alternative | news.ycombinator.com | 2026-01-14

    You can have a try; almost all sota models are supported all powered thanks to https://github.com/camel-ai/camel

24. LangBot

    23 4 16,282 9.9 Python

    ChatGPT chat bot for Tencent QQ, based on mirai and OpenAI API.

    

    Project mention: Preview your coding agents' work without painful CIs or servers; just paste a prompt | dev.to | 2026-05-05

    Trying to preview a WIP branch of LangBot :

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