Hail
web
Hail | web | |
---|---|---|
5 | 157 | |
935 | 1,768 | |
0.6% | 0.4% | |
9.8 | 6.4 | |
7 days ago | 9 months ago | |
Python | JavaScript | |
MIT License | GNU General Public License v3.0 or later |
Stars - the number of stars that a project has on GitHub. Growth - month over month growth in stars.
Activity is a relative number indicating how actively a project is being developed. Recent commits have higher weight than older ones.
For example, an activity of 9.0 indicates that a project is amongst the top 10% of the most actively developed projects that we are tracking.
Hail
- We're wasting money by only supporting gzip for raw DNA files
-
Software engineers: consider working on genomics
I don't have any funding to hire right now, but I'm always happy to chat about the industry and my experience building Hail (https://hail.is, https://github.com/hail-is/hail), a tool widely used by folks with large collections of human sequences.
The other posters are not wrong about compensation. Total compensation is off by a factor of two to three.
However, it is absolutely possible to work with a group of top-notch engineers on serious distributed systems & compilers in service of an excellent scientific-user experience. I know because I do. We are lucky to have a PI who respects and hires and diversity of expertise within his lab.
I enjoy being deeply embedded with our users. I do not have to guess what they need or want because I help them do it every day.
I also enjoy enmeshing engineering with statistics, mathematics, and biology. Work is more interesting when so many disciplines conspire towards the end of improved human health.
-
AWS doesn't make sense for scientific computing
I think this post is identifying scientific computing with simulation studies and legacy workflows, to a fault. Scientific computing includes those things, but it also includes interactive analysis of very large datasets as well as workflows designed around cloud computing.
Interactive analysis of large datasets (e.g. genome & exome sequencing studies with 100s of 1000s of samples) is well suited to low-latency, server-less, & horizontally scalable systems (like Dremel/BigQuery, or Hail [1], which we build and is inspired by Dremel, among other systems). The load profile is unpredictable because after a scientist runs an analysis they need an unpredictable amount of time to think about their next step.
As for productionized workflows, if we redesign the tools used within these workflows to directly read and write data to cloud storage as well as to tolerate VM-preemption, then we can exploit the ~1/5 cost of preemptible/spot instances.
One last point: for the subset of scientific computing I highlighted above, speed is key. I want the scientist to stay in a flow state, receiving feedback from their experiments as fast as possible, ideally within 300 ms. The only way to achieve that on huge datasets is through rapid and substantial scale-out followed by equally rapid and substantial scale-in (to control cost).
[1] https://hail.is
-
Ask HN: Who is hiring? (July 2021)
Broad Institute of MIT and Harvard | Cambridge, MA | Associate Software Engineer | Onsite
We are seeking an associate software engineer interested in contributing to an open-source data visualization library for analyzing the biological impact human genetic variation. You will contribute to projects like gnomAD (https://gnomad.broadinstitute.org), the world's largest catalogue of human genetic variation used by hundreds of thousands of researchers and help us scale towards millions of genomes in the coming years. We are also developing next-generation tools for enabling genetic analyses of large biobanks across richly phenotyped individuals (https://genebass.org). In this role you will gain experience developing data-intensive web applications with Typescript, React, Python, Terraform, Google Cloud Platform, and will make use of the scalable data analysis library Hail (https://hail.is). Key to our success is growing a strong team with a diverse membership who foster a culture of continual learning, and who support the growth and success of one another. Towards this end, we are committed to seeking applications from women and from underrepresented groups. We know that many excellent candidates choose not to apply despite their capabilities; please allow us to enthusiastically counter this tendency.
Please provide a CV and links previous work or projects, ideally with contributions visible on Github.
email: [email protected]
web
-
Octant is donating 1M in ETH to 10 public goods projects, and you can help decide how to allocate.
Here's the list of projects you can support: Clr.fund - https://clr.fund/ DAO Drops - https://daodrops.io/ Drips - https://www.drips.network/ Ethereum Cat Herders - https://www.ethereumcatherders.com ETHStaker - https://ethstaker.cc Giveth - https://giveth.io/ Gitcoin - https://gitcoin.co Kernel - https://www.kernel.community/en/ Protocol Guild - https://protocol-guild.readthedocs.io Supermodular - https://supermodular.xyz/
-
Daily General Discussion - April 12, 2023
The Gitcoin website has some of the worst information architecture, I have no idea what their team is doing. I can't imagine how many people visited gitcoin.co to donate and couldn't figure out how.
- Thoughts on building an ETH dominated portolio?
-
Best Websites For Coders
GitCoin : Gitcoin is the easiest way to monetize or incentivize work in Open Source Software.
-
Do you as a socialist consider blockchain tech as a path towards a worker-owned means of production? It’s the primary goal of many crypto projects.
Also, check out Gitcoin: https://gitcoin.co/ (which coincidentally does have a token) but has funneled over $65m directly to open source software developers. They’ve also recently formed a foundation that is governed by the token holders.
-
How can i work online for crypto?
Check out https://gitcoin.co/!
-
The Importance of Cryptocurrency to Web 3 and the Future of Decentralization
If you want to get involved then I suggest going to https://gitcoin.co/
-
Reminder for people interested in Bisq to get involved in discussing proposals on GitHub
There's other projects that have tried implementing something similar though.
-
Nano bounty program
Check out https://gitcoin.co. They provide a platform for web3 projects to provide bounties to people creating for projects.
-
Making money with ethdev projects?
gitcoin.co has bounties and hackathons with prizes.
What are some alternatives?
GridScale - Scala library for accessing various file, batch systems, job schedulers and grid middlewares.
opensea-js - TypeScript SDK for the OpenSea marketplace
Vegas - The missing MatPlotLib for Scala + Spark
rotki - A portfolio tracking, analytics, accounting and management application that protects your privacy
metorikku - A simplified, lightweight ETL Framework based on Apache Spark
openzeppelin-contracts - OpenZeppelin Contracts is a library for secure smart contract development.
Scoozie - Scala DSL on top of Oozie XML
hevm - Dapp, Seth, Hevm, and more
Jupyter Scala - A Scala kernel for Jupyter
Gravitational Teleport - The easiest, and most secure way to access and protect all of your infrastructure.
Summingbird - Streaming MapReduce with Scalding and Storm
quadratic-funding - This is an open source implementation of quadratic funding, a design for philanthropic and publicly-funded seeding, which allows for optimal provisioning of funds to an ecosystem of public goods.