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How about fpdf2?
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Judoscale
Save 47% on cloud hosting with autoscaling that just works. Judoscale integrates with Django, FastAPI, Celery, and RQ to make autoscaling easy and reliable. Save big, and say goodbye to request timeouts and backed-up task queues.
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I have used WeasyPrint in the past, it worked very well for the use case I had, which was basically a service that transforms HTML into PDF, it follows the W3C specification that is recommend for print (you can actually generate Headers and Footers that repeats every page, something that chrome doesn't do)
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gotenberg
A developer-friendly API for converting numerous document formats into PDF files, and more!
https://gotenberg.dev - this is what I use now, you can host your own and have all your clients use it via API calls (just post an html + CSS file and it returns a PDF)
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What you want is not Python, its R Markdown; https://rmarkdown.rstudio.com/
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You might take a look at borb
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InfluxDB
InfluxDB high-performance time series database. Collect, organize, and act on massive volumes of high-resolution data to power real-time intelligent systems.