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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
The latest tutorial with type-hinting is the "new" one, but this is if you wanted to follow the tutorial. To review the code itself you should look at the GitHub repository instead. This tutorial was written for Python 3.7.
I think https://github.com/python/typing/issues/553 suggests a possible answer to #1.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.