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Insight Toolkit (ITK) -- Official Repository. ITK builds on a proven, spatially-oriented architecture for processing, segmentation, and registration of scientific images in two, three, or more dimensions.
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It also depends heavily on the toolchain. One of the first successful toolkits used to circumvent image-based security measures was ITK, originally a toolkit for medical image processing. That's not even using AI (at least back then). Here you build "piplines" by lego'ing together functions like building blocks, there are rules to it, but the sleek interface design make it very versatile. It was a nightmare to devise ways to counteract, since the crucial processing steps could easily be switched around as long as the linear algebra made sense. And when you have a toolchain excelling in fourier-space based analysis and interaction, the linear algebra makes sense in a lot of different orders of doing steps.