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BOLT
Discontinued Binary Optimization and Layout Tool - A linux command-line utility used for optimizing performance of binaries (by facebookarchive)
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
If you're just excited to try out some shiny things then you can take a look at https://github.com/facebookincubator/BOLT, which is like PGO AFAIU. But again, in would definitely help if you have some elisp snippet that would measure the performance you care about so that you can see how much things improved after you enable a flag like -O3 or apply a tool like BOLT.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.
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