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For quadratic programming—which is a class of problems in convex optimization, which is a sub-field of numerical optimization in general—a solver that is frequently used is OSQP. Although it is implemented in C++ you can also use it in Python thanks to its bindings. If your goal is to use a solver that's state-of-the-art and relatively versatile it is a good pick. If your goal is to find the best solver for a given problem, then there is no one-stop-shop. For example in this benchmark OSQP was the best-performing solver for sparse problems but quadprog performed better on dense problems.
For quadratic programming—which is a class of problems in convex optimization, which is a sub-field of numerical optimization in general—a solver that is frequently used is OSQP. Although it is implemented in C++ you can also use it in Python thanks to its bindings. If your goal is to use a solver that's state-of-the-art and relatively versatile it is a good pick. If your goal is to find the best solver for a given problem, then there is no one-stop-shop. For example in this benchmark OSQP was the best-performing solver for sparse problems but quadprog performed better on dense problems.