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Iron python
Implementation of the Python programming language for .NET Framework; built on top of the Dynamic Language Runtime (DLR).
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Depending on how you want to handle things, you could use something like https://ironpython.net/, but Newt is correct in that you'll probably want some sort of restful backend in Python.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.
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