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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Also check out Python Development Master which supports PEP 582. It does not use virtual environment at all. It installs and manages packages in a similar way to npm that doesn't need to create a virtualenv. This is a next generation dependency management.
culture of authoring packages like this rather than just writing it oneself
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.