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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
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maturin
Build and publish crates with pyo3, cffi and uniffi bindings as well as rust binaries as python packages
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SaaSHub
SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives
Arch: yay -S gtk3-classic lib32-gtk3-classic
If you do need more dependencies, don't want to use Flatpak, and do want easy installation, the PyPI PyQt5 package includes a manylinux2014 wheel that Pipenv or Poetry or PyInstaller could pull in. (Granted, you'll need to run PyInstaller in the manylinux2014 Docker container if you don't want to bake in a "minimum glibc version" dependency on whatever glibc your system has.)
maturin makes it really easy to build a rust-cpython or PyO3 module into a wheel so distributing a mixed Rust-Python project is no more difficult than a pure Python project as long as you upload wheels for all the platforms you want to support.
If you want a single build that works on all Linux distros, before you discount PyQt, consider borrowing the PyQt5 recipe from the Tor Browser Launcher's Flatpak definition? You can't really get easier than putting a Flatpak up on Flathub. (Though, granted, Ubuntu-family distros do require a couple of lines copy-pasted from Flathub into the terminal to add Flatpak first.)
I haven't checked if it works with PyQt yet, but PyOxidizer (introduction blog post) is a Rust+rust-cpython tool intended to make building self-contained Python distributables simple and easy.