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This is not true for all crypto coins. A small proportion of mining hash functions are deliberately designed to thwart ASICs, e.g. https://github.com/tevador/RandomX. It's a cat-and-mouse game, though: CryptoNight was designed to fulfill the same role, but ultimately failed: https://monerodocs.org/proof-of-work/cryptonight/.
My personal recommendation would be Folding@Home[1]. Protein folding is an insanely complex thing life does and they use distributed computing to try to solve the large problems.
1. https://foldingathome.org/?lng=en
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.
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