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InfluxDB
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I'd check out what https://www.specialeffect.org.uk/ do - they do a lot of work attempting to make all games accessible via custom hardware, it's amazing. And, like other commenters have suggested, Microsoft have their "Adaptive Controller" to make it easier to create custom controller setups for your GFs daughter's specific needs i.e. it allows you to add all sorts of different input modules via 3.5mm jacks. Sony were a little slower off the mark than Microsoft in this regard, but they've just this year announced "Project Leonardo", which is their entry into the accessible controller field.