Illumina's Manta candidateSmallIndels.vcf.gz Fed Into Illumina's Strelka Using What Sample's candidateSmallIndels.vcf.gz Experimental/Tumor or Normal?

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  • strelka

    Strelka2 germline and somatic small variant caller (by Illumina)

  • For the Illumina's Strelka code I see something a bit confusing in the somatic configuration example shown below as well as in the url given.

  • manta

    Discontinued Structural variant and indel caller for mapped sequencing data (by Illumina)

  • It says it uses the `candidateSmallIndels.vcf.gz` created by Illumina's Manta however, I cannot seem to find information as to if this `candidateSmallIndels.vcf.gz` is created by Manta using the tumor bam or the normal. Does anyone perchance know which sample was used in creation of the `candidateSmallIndels.vcf.gz` used here? As `candidateSmallIndels.vcf.gz` seems to be made per sample from what I understand of Illumina Manta's documentation?

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