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I don't think there's a best per say, but we did recently use Objection on our project. Did the job well, only issue is there's no constructor for the DB Models but it's just something you work around (https://vincit.github.io/objection.js/)
If you want to just write raw/valid SQL safely - SafeQL is great, one major issue though is that it doesn't work on Windows (you can hack it with WSL).
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