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Win2D
Win2D is an easy-to-use Windows Runtime API for immediate mode 2D graphics rendering with GPU acceleration. It is available to C#, C++ and VB developers writing apps for the Windows Universal Platform (UWP). It utilizes the power of Direct2D, and integrates seamlessly with XAML and CoreWindow.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Your easiest bet is likely to use Win2D within UWP or WinUI 3, then you could just throw a CanvasControl as the root of your UI and draw whatever you want on it, including setting individual pixels. Alternatively an easy way to do that could be to use a WriteableBitmap in WPF/UWP/WinUI 3 just drawn into a root Border or something, and then you can easily manipulate pixels there. Of course, that'd be slower and not CPU accelerated, but still viable depending on your exact use case.