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flet
Flet enables developers to easily build realtime web, mobile and desktop apps in Python. No frontend experience required.
Django Unicorn is the closest thing that answers the question IMO. Personally, I've never used it since I don't want to lock myself into a Django-only way of doing things (at least, more often than I have to).
If you can do SSR/SSG, I highly recommend Astro.
I'm all of these suggestion have value. But I thought I'd bring up a new tool written in python 'Flet'. flet.dev. It is based on flutter which is built to create frontends.