nimbus-eth1 VS mosdepth

It certainly seems it will be remembered as a major success story for open p2p protocols on the global Internet of our time.

A great multitude of developers and enthusiasts belonging or contributing to diverse teams spread across the world: developing, debating, and collaborating for years to arrive at the big event.

And it's all been done very much in the public view:

https://weekinethereumnews.com/

https://hackmd.io/@benjaminion/eth2_news

https://github.com/ethereum/pm

https://www.youtube.com/c/EthereumFoundation/videos

Consensus Clients:

https://github.com/sigp/lighthouse#readme

https://github.com/ChainSafe/lodestar#readme

https://github.com/status-im/nimbus-eth2#readme

https://github.com/prysmaticlabs/prysm#readme

https://github.com/ConsenSys/teku#readme

Execution Clients:

https://github.com/akula-bft/akula#readme

https://github.com/hyperledger/besu#readme

https://github.com/ledgerwatch/erigon#readme

https://github.com/ethereum/go-ethereum#readme

https://github.com/NethermindEth/nethermind#readme

https://github.com/status-im/nimbus-eth1#readme

https://github.com/status-im/nimbus-eth1 (yes, this is also for eth2, see "About" at top right)

I expect we will see a "merged" client in the future. Nimbus could be the closest of anyone to this vision (nimbus-eth1, nimbus-eth2). Not sure when this will happen though. Anyways, you have to remember -- these are two extremely complicated pieces of software. Just the interface between the two has been developed and tests over the last 18 months. I think there will always need to be serious encapsulation of logic for it to be maintainable.

I'm not sure why that happens, but an alternative to bedtools genomecov is mosdepth. Maybe you can try that tool instead as it's very reliable.

I would give mosdepth a look. It can provide depth across a chromosome/contig at each base, or a mean depth for a given window size (eg 1kb), or regions provided within a bed file, or a simple summary of the mean depth across each chromosome/contig.