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FlingOS
Discontinued An educational operating system written in C#. A great stepping stone from high to low level development.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
You can do everything in C in C#. Including raw pointers. It's not commonly done, but the functionality is all there. The hardest part is getting it all compiled, ahead-of-time, down to machine code. But lots of people online have done that before so it's effectively a solved problem.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.