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ASP.NET Core
ASP.NET Core is a cross-platform .NET framework for building modern cloud-based web applications on Windows, Mac, or Linux.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Look at it this way, Learn VB in school, keep learning c# on your own, learn asp.net core and add .net framework if you can.. learning vb might seems stupid but it will boost your chances of getting a job.
i know two frameworks to build a really strong and modern desktop interface in C#:- Bunifu- Guna
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.