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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Have a look at this: https://github.com/Scott-Cooper/Drawbot_image_to_gcode_v2 -- it uses processing and is configured to use Copic markers; separating the image into different plates/layers that you'd run after manually swapping the pens. I have not run it multi-color, only used it for the single color processing option.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.