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dtype-next
A Clojure library designed to aid in the implementation of high performance algorithms and systems.
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Learn and use specter for nested data manipulation, will take some studying but is a more general solution (https://github.com/redplanetlabs/specter)
If this is something common and the work is numeric, I would highly recommend exploring dtype-next buffer abstraction and tensors. The tensor api supports a nice APL-like substrate for working in index space without having to have the underlying storage "be" a boxed datastructure. You also get the option of off-heap / native tensors that can be zero-copy shuttled between other runtimes.