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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
The three first clients in the joinmastodon site:
Tusky: https://github.com/tuskyapp/Tusky
Fedilab: https://framagit.org/tom79/fedilab/
SubwayTooter: https://github.com/tateisu/SubwayTooter
All of them are foss and developed by a single person or a small team.
As for the system requirements. Mastodon might be a bit heavy but you could try another server software with activitypub support.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.