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If the issues persist with up-to-date filters, report them either on https://github.com/uBlockOrigin/uAssets/issues or /r/uBlockOrigin and they'll probably get fixed.
About the Twitch ads, this has nothing to do with any adblocker in specific, uBlock Origin is still the best one out there. You just need to use the dyn-skip-midroll-alt script for uBO from https://github.com/pixeltris/TwitchAdSolutions and you'll not see ads until Twitch patches this properly.
And fortunately, uBO is not part of that class -- and to keep repeating this is not going to make it true. By the look of it, the extension you suggest does not seem to be actively developed -- including your own issues which have been left unanswered for quite a while now; while the other extension you suggest has not been updated in nearly three years, with development halted.