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You can check our uECG project - it's open source, main code is located here https://github.com/ultimaterobotics/uECG (and there are several links to other our repositories for radio library, bootloader and other stuff). It is a single channel ECG.
I in fact wrote a library for nrf52 family that, among other things, handles my own RF protocol (https://github.com/ultimaterobotics/urf_lib although no documentation yet) - I'm using star architecture, one central node talking to multiple peripherals at close to realtime schedule - communication cycle time is <2 ms per connected device, variable payload up to 250 useful bytes, no in-built acks or retransmits. That's because I had the need for such pattern in multiple projects I worked on.