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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
I've found Fastmate to be a really great alternative to a traditional desktop client for Mac, with notifications, the ability to set it as your default mail client, and an app badge for unread email. It's free and open source.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.