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InfluxDB
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If you're fine with Javascript you can have a look at https://github.com/ledgerhq/ledgerjs which is the most maintained transport library to communicate with the different device applications (f.e. https://github.com/LedgerHQ/ledgerjs/tree/master/packages/hw-app-eth for Ethereum)
If you want to see the raw communication protocol, it's usually described in the source code of the device application itself - f.e. for Ethereum you'll find it in https://github.com/LedgerHQ/app-ethereum/blob/master/doc/ethapp.asc and sample Python code to sign a transaction in https://github.com/LedgerHQ/app-ethereum/blob/master/examples/signTx.py