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ClosedXML
ClosedXML is a .NET library for reading, manipulating and writing Excel 2007+ (.xlsx, .xlsm) files. It aims to provide an intuitive and user-friendly interface to dealing with the underlying OpenXML API.
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I tend to use ClosedXML if I'm doing work with Excel. It does only do Excel files, though, so you'd have to find something else if you want to work with Word/PP/whatever.
ClosedXML works great. Also worth taking a look at ExcelDataReader if you want a simple lightweight solution for parsing excel and csv files with a single library.
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