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Tailwind CSS will give you full control over your design because they are just utility classes. Tailwind framework is like bootstrap with predefined style out of the box. We use tailwind for working in custom designs so currently I suggest you try out Tailwind CSS.
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SaaSHub
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Tailwind is a great option to look into, I really enjoy it, but if you want something a bit more in-between, you can check out frameworks like https://www.pollen.style. There you get a framework of consistent CSS variables you can use, while still writing all your vanilla CSS yourself with full control of everything.
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I struggled a lot to understand it, until my former tech lead sent me this: https://flexboxfroggy.com/
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Using an SCSS pre-processor gives you access to powerful math and nice tools, like https://eduardoboucas.github.io/include-media/ for example.