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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
I don't have experience with Factset, but I've worked with ISINs a lot, mainly in the Indian context. Depending on which country you are dealing with, you could look at the relevant issuer. I've found OpenFIGI to be reasonably good, with batch-based querying, and a proper API, so that might work for your usecase.
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