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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
Plus, CerBios added support for compressed ISO images (.CCI files), which reduces the size of each ISO by a notable amount. So if you're using CerBios and don't mind compressing your library using Repackinator, that reduces the need for a huge HDD (>4TB). But this app requires you to already have a redump image of each game (unless they've updated it since I last tried).
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.