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Stream
Stream - Scalable APIs for Chat, Feeds, Moderation, & Video. Stream helps developers build engaging apps that scale to millions with performant and flexible Chat, Feeds, Moderation, and Video APIs and SDKs powered by a global edge network and enterprise-grade infrastructure.
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Cypht
Cypht: Lightweight Open Source webmail aggregator [PHP, JS]. Supports IMAP/SMTP, JMAP and EWS (Exchange Web Services)
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Mailspring
:love_letter: A beautiful, fast and fully open source mail client for Mac, Windows and Linux.
I love Mailspring, it's modern and open source: https://getmailspring.com/
The UI uses Electron, but the actual sync engine is in C++, so it's pretty fast.
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email-oauth2-proxy
An IMAP/POP/SMTP proxy that transparently adds OAuth 2.0 authentication for email clients that don't support this method.
If you use this proxy of mine then any IMAP (or POP/SMTP) client can be used with a “modern” email provider, regardless of whether it supports OAuth 2.0 natively: https://github.com/simonrob/email-oauth2-proxy
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We should pay very close attention to https://github.com/nostr-protocol/nostr as I think the future of app development is letting multiple clients implement their own custom UI layers on top of a shared core.