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It seems that Intel is currently 404ing the I remember in the 82579LM datasheet regarding firmware made a vague reference to the Intel ME being used the PXE boot. If the ME parition has neutered or the generated GBE partition is being used, this shouldn't be a concern.
If you asking about the reference in the me_cleaner readme about full network access, this is less to do ME and more how it integrates with other Intel platforms. ME requires network access for platforms like Intel AMT. If your network card does not support enterprise level remote administration feature like AMT, you have nothing to worry about. If you ran ME cleaner, you also have nothing to worry about.